Nene led the Wizards with 16 points.
Emeka Okafor added 15 points and a season-high 17 rebounds.
Martell Webster also scored 15 points in the loss.
Okafor was 7-15 shooting on the night.
Webster grabbed only two boards on the night, but made his presence felt on offense.
Okafor has been active down low for the Wizards.
Okafor with the slam.
It was a quiet night for John Wall, scoring only 9 points against the Sixers.
Nene shot 50 percent from the floor against the Sixers.
Garrett Temple got the start in place of Bradley Beal, who is out with a sore wrist.
Kevin Seraphin added 8 points.
Behind the scenes at the NBA Draft Lottery with Bradley Beal and Ernie Grunfeld.
Caps fall in game seven to the Rangers, 5-0.
Caps fall to the Rangers in game six, 1-0.
2013 Mystics Media Day photos
The best photos from John Wall's 2012-13 season.
Wizard Girls photos from the 2012-13 season.
Caps take game 5 as Mike Ribeiro scores in OT for the 2-1 win.
Bradley Beal's rookie year in photos.
Day 2 of Mystics Training Camp.
The Mystics win over the Brazil National Team in a preseason content, 71-56.
Photos from Monday's Mystics practice.
Photos from Thursday's morning and night practice.
The Caps fell to the Rangers in game four in New York, 4-3.
The Caps fall to the Rangers in game three at MSG, 4-3.